25-Hydroxycholesterol stimulates sphingomyelin synthesis in Chinese hamster ovary cells.
نویسندگان
چکیده
منابع مشابه
Chinese hamster ovary cells overexpressing the oxysterol binding protein (OSBP) display enhanced synthesis of sphingomyelin in response to 25-hydroxycholesterol.
25-Hydroxycholesterol negatively regulates cholesterol synthesis and activates cholesterol esterification in a variety of cultured cells. Concurrent with these effects, 25-hydroxycholesterol also stimulates the synthesis of sphingomyelin in Chinese hamster ovary (CHO)-K1 cells. The role of oxysterol binding protein (OSBP), a high affinity receptor for 25-hydroxycholesterol, in activation of SM ...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 1995
ISSN: 0022-2275
DOI: 10.1016/s0022-2275(20)41142-3